Non-Neoplastic Breast Lesions in an Adult Female Population in Niger Delta Region of Nigeria
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Abstract
Introduction: Non-neoplastic breast lesions are common in adult females, causing significant anxiety and concern. These lesions can be radiologic and clinical mimics of breast cancer, therefore making accurate histological diagnosis crucial to exclude malignancy and inform management decisions. The aim of this study was to To analyse the spectrum of non-neoplastic breast lesions in female adults, exploring age-related patterns and diagnostic methods.
Methods: A retrospective descriptive study of 378 adult female patients with non-neoplastic breast lesions who underwent histopathological evaluation at the University of Port Harcourt Teaching Hospital between 2013 and 2022.
Results: Fibrocystic change was the most prevalent diagnosis (69.6%), which was more prevalent in women aged 20-50 years. Chronic non-specific mastitis (5.4%) and breast abscesses (3.1%) were also seen. Atypical ductal hyperplasia (1.3%) was also seen and was more prevalent in women aged 40-59 years. Excisional biopsies were the preferred diagnostic method (91.5%).
Conclusion: This study highlights the importance of recognizing non-neoplastic breast lesions, particularly fibrocystic changes, and optimizing diagnostic approaches. Targeted surveillance for atypical ductal hyperplasia and prompt treatment of inflammatory conditions can improve patient outcomes.
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